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Ceraplex Ingredients:

Curcumin

Curcumin (CUR): The active polyphenol compound in the bright yellowish orange spice, Turmeric, CUR is a powerful COX-2 inhibitor. It may also reduce brain inflammation via other pathways such as, LOX-5 as well as highly damaging NOS (nitric oxide) based peroxynitrites.CUR is also a powerful anti-oxidant and neuro-protective agent.

References:

Subramanian M, Sreejayan, Rao MN, Devasagayam TP, Singh BB. Diminution of singlet oxygen-induced DNA damage by curcumin and related antioxidants. Mutat Res 1994; 11:249–255.

Mukundan MA, Chacko MC, Annapurna VV, Krishnaswamy K. Effect of turmeric and curcumin on BP-DNA adducts. Carcinogenesis ( Oxford) 1993; 14:493–496.

Huang MT, Lysz T, Ferraro T, Abidi TF, Laskin JD, Conney AH. Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res 1991; 51: 813–819.

Zhao BL, Li XJ, He RG, Cheng SJ, Xin WJ. Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals. Cell Biophys 1989; 14:175–185.

Ramsewak RS, DeWitt DL, Nair MG. Cytotoxicity, antioxidant and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine ( Jena) 2000; 7:303–308.

Yamamoto H, Hanada K, Kawasaki K, Nishijima M. Inhibitory effect of curcumin on mammalian phospholipase D activity. FEBS. Letters 1997; 417:196–198.

Scapagnini G, Foresti R, Calabrese V, Giuffrida Stella AM, Green CJ, Motterlini R. Caffeic acid phenethyl ester and curcumin: A novel class of heme oxygenase-1 inducers. Mol Pharmacol 2002; 61:554–561.

Soliman KFA, Mazzio EA. In vitro attenuation of nitric oxide production in C6 astrocyte cell culture by various dietary compounds. Proc Soc Exp Biol Med 1998; 218:390–397.

Frautschy SA, Hu W, Kim P, Miller SA, Chu T, Harris-White ME, Cole GM. Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology. Neurobiol Aging 2001; 22:993–1005.

Rowe B, Ronzio RA, Wellner VP, Meister A. Glutamine Synthetase (Sheep Brain). Meth Enzymol 1970; 17:900–902.

Prohaska JR, Clark DA, Wells WW. Improved rapidity and precision in the determination of brain 2’,3’-cyclic nucleotide 3’- phosphohydrolase. Anal Biochem 1973; 56:275–82.

 

 
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.